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The high affinity calcitonin receptor encoded by this gene is a member of a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein controls osteoclast-mediated bone resorption and helps to maintain calcium homeostasis. The onset of osteoporosis and differences in bone mineral density have been linked to polymorphisms in this gene. Multiple transcript variations result from alternative splicing.
For more: https://www.antibody-creativebiolabs.com/symbolsearch-calcr.htm
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